Relationship between residual kidney function and symptom burden in haemodialysis patients

BACKGROUND Residual kidney function (RKF) has been associated with improved solute clearance and survival in haemodialysis (HD) patients. However, whether RKF impacts symptom burden HD patients is unknown. AIMS To determine the prevalence of to explore associations between higher levels burden, as well clinical biochemical parameters. METHODS This a single-centre, retrospective, observational study. was assessed urea (KRU) by interdialytic urine collection. Symptom measured using palliative care outcome scale renal questionnaire. RESULTS A total 90 maintenance recruited; 31.9% had KRU ?1 mL/min/1.73?m2 . Patients reported fewer symptoms (5.3 ±?3.5 vs 7.7 ±?3.8) (P =?0.011), including less shortness breath (15% 55%) =?0.0013) vomiting (0% 30%) =?0.0016). Higher lower ?2 -microglobilin <?0.0001), serum potassium =?0.02), but no difference phosphate, haemoglobin, C-reactive protein or albumin. CONCLUSION significantly symptoms, -microglobulin potassium, suggesting that strategies preserve may be beneficial.